For breast cancer patients, improved screening and treatment outcomes have increased survival. The number of breast cancer survivors is already over 3 million, and by 2030, it is expected to reach over 5 million. The average 5-year survival rate for breast cancer patients is 90%. This requires a multidisciplinary approach involving a primary care doctor, an oncologist, a radiation oncologist, a pharmaco-oncologist, and frequently a cardio-oncologist. The Cardio-Oncology team's mission is to make sure patients may receive the best cancer treatment while reducing their risk of heart problems and managing any heart abnormalities that may develop as a result of the cancer treatment.
Which Breast Cancer Patients Are
Prone to Cardiovascular Issues?
The
number one cause of death for both men and women in the general population is
cardiovascular disease (CVD). However, compared to age-matched controls,
individuals with breast cancer have an even higher rate of CVD. This is
probably because breast cancer and cardiovascular disease risk factors are
connected, in addition to cancer-related treatments. Importantly, managing
cardiovascular risk factors and coexisting conditions improves breast cancer
survival while also reducing cardiovascular morbidity and mortality.
It
is possible to distinguish between patient-related risk factors and
medication-related hazards when determining a patient's risk for cardiac
problems due to breast cancer.
There
is an increased risk of cardiac events in women over the age of 60, as well as
in those with hypertension, diabetes mellitus, obesity, high cholesterol,
smoking, coronary artery disease, peripheral artery disease, heart failure,
cardiomyopathy, atrial fibrillation, prior anthracycline treatment, or chest
radiation.
What Cardiovascular Conditions Are
Most Commonly Associated With Breast Cancer Treatment?
The
development of cardiomyopathy and systolic heart failure in individuals
receiving chemotherapy drugs like anthracycline is one of the most significant
cardiac side effects (Doxorubicin or Epirubicin). It is known that
anthracyclines cause topoisomerase inhibition, apoptosis, mitochondrial damage,
and increased oxidative stress. This may begin as an asymptomatic decline in
heart function (lower Ejection Fraction), and it may develop into systolic
heart failure. A cumulative dose of 250 mg/m2, a dose of 14 mg/m2, and a dose
of 400 mg/m2 all result in an exponential rise in this risk: 6%, 14%, and 33%,
respectively. Combining cyclophosphamide with another drug increases the risk
as well.
How Can the Risk Be Minimized?
Adopting
a healthy lifestyle is among the most vital elements in minimizing cardiac
problems after breast cancer treatment. Exercising for 30 to 45 minutes five
days a week, alternating it with strength training, yoga, and stretches.
Examples of aerobic exercises are brisk walking, swimming, and cycling. Eating
a balanced diet that avoids processed meat and refined sugar while including
fruits and green leafy vegetables. To prevent coronary artery disease, it is
essential to treat diabetes mellitus, hypertension, and hyperlipidemia as well
as to stop smoking.
CPR Class Memphis has
been guiding participants with the latest techniques to deal with the victims
of choking and breathing. The hands-on live training seems to be extremely
helpful for uplifting the confidence level of the students.
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